The Use of a Jet-PhoresisTransdermal Delivery System for Pain Control – ASLMS 2010

What is JetPeel?

• A treatment based on supersonic delivery of materials, including actives, to the skin
• Ability to simultaneously introduce active nutrients and oxygen into the skin, using pressure and air

Current Study Design:

• Prospective clinical study to compare lidocaine jet-phoresis trans-cutaneous anesthesia to EMLA 5% topical cream
• 20 patients that were scheduled to undergo needling roller for upper lip rhytids enrolled into study
• Each patient served as own control – 40 lips evaluated
• Half of the upper lip had EMLA 5% cream applied for 45 minutes
• Contra-lateral portion of the lip treated with lidocaine 3% jetphoresis for 5 minutes
• Pain elicited with needling roller uniformly applied across the upper lip
• Pain response measured using VAS scale

Background: Basic Principles

• Pressurized gas is used to accelerate a liquid agent (saline).
• Water droplets accelerated to supersonic velocities (200 m/s)
• The mixture of liquid and gas is emitted through a special nozzle unit.
• The high velocity jet exfoliates the superficial layers of the skin